The discovery is the thing

The discovery is the thing

Photo by Sangharsh Lohakare on Unsplash

Originally published 21 January 2003

Which of the fol­low­ing works would you choose to be lost, if only three could be saved: Michelan­gelo’s Pietà, Shake­speare’s Ham­let, Mozart’s Don Gio­van­ni, or Ein­stein’s 1905 paper on relativity.

French micro­bi­ol­o­gist Antoine Danchin asks this ques­tion (with one incon­se­quen­tial dif­fer­ence) in his book, The Del­ph­ic Boat: What Genomes Tell Us.

The answer is easy, he says. Trash Ein­stein’s paper.

Not because Ein­stein’s the­o­ry of rel­a­tiv­i­ty is any less cre­ative or any less impor­tant than the works of Michelan­ge­lo, Shake­speare, or Mozart. In the long run, rel­a­tiv­i­ty may be vast­ly more impor­tant than the work of any artist.

If Ein­stein had not invent­ed rel­a­tiv­i­ty, how­ev­er, some­one else would have done so. The idea was in the air in 1905. Soon­er or lat­er, every detail of Ein­stein’s work would have been achieved by some­one else, or some group of people.

The same is true of most big break­throughs in sci­ence. New­ton’s the­o­ry of uni­ver­sal grav­i­ta­tion was prob­a­bly inevitable in the late-17th cen­tu­ry, if not from New­ton then from Robert Hooke, say, or Got­tfried Leib­nitz. Dar­win’s the­o­ry of evo­lu­tion by nat­ur­al selec­tion was con­ceived simul­ta­ne­ous­ly by Alfred Rus­sel Wallace.

But if Michelan­ge­lo, Shake­speare, or Mozart had not lived, the works of their par­tic­u­lar genius­es would be lost forever.

And so, Danchin says, we can dump Ein­stein’s 1905 paper on rel­a­tiv­i­ty in con­fi­dence that the ulti­mate course of sci­en­tif­ic dis­cov­ery would have been more or less unchanged.

Per­haps there are oth­er rea­sons to pre­fer the artists to Ein­stein. The Pietà, Ham­let, and Don Gio­van­ni do not, as far as I know, have a down­side. Rel­a­tiv­i­ty, on the oth­er hand, had its most dra­mat­ic con­fir­ma­tion in the hor­rif­ic destruc­tion of Hiroshi­ma and Nagasa­ki. The shad­ow of Ein­stein’s bril­liant idea hangs over sub­se­quent his­to­ry like a dark cloud.

But rel­a­tiv­i­ty also explains the Big Bang, how the stars shine, and why the uni­verse is filled with light and life. Would we real­ly want to live with­out that knowl­edge? Is the Pietà more impor­tant than the secret of the sun? Is Ham­let worth the knowl­edge of how the uni­verse began?

Clear­ly, to equate a work of sci­en­tif­ic cre­ativ­i­ty with a work of art is apples and oranges. The respec­tive acts of cre­ativ­i­ty may have much in com­mon, but the prod­ucts of cre­ativ­i­ty in art and sci­ence are of a dif­fer­ent nature.

Con­sid­er genet­ics, the sub­ject of Antoine Danch­in’s book men­tioned above.

Per­haps the most impor­tant sci­en­tif­ic dis­cov­ery of my life­time was the dou­ble-helix struc­ture of DNA by James Wat­son, Fran­cis Crick, and Ros­alind Franklin, at Cam­bridge Uni­ver­si­ty in the 1950s.

The sci­en­tists knew they were in a race, and they knew the prize — the secret of life. The struc­ture of DNA was a prob­lem ready to be solved. Var­i­ous indi­vid­u­als and teams of sci­en­tists in the Unit­ed States and Europe were work­ing hard to put the data togeth­er and draw the appro­pri­ate con­clu­sion. A par­tic­u­lar­ly sug­ges­tive X‑ray pho­to­graph of DNA by Franklin was the key that let Wat­son and Crick cop the prize.

Of course, Michelan­ge­lo was in some­thing of a com­pe­ti­tion, too, with his artis­tic rivals, Leonar­do, Raphael, and Tit­ian. In the end, the artists were all win­ners. But DNA has a unique struc­ture, and only one sci­en­tist or team of sci­en­tists could be the discoverer.

And what a dis­cov­ery! That all of life shares the same “four-let­ter” chem­i­cal code, arrayed along a wind­ing stair­case mol­e­cule that unzips down the mid­dle to copy itself, or to string amino acids togeth­er into pro­teins — mol­e­c­u­lar machin­ery of stun­ning sim­plic­i­ty that weaves a liv­ing fab­ric of almost infi­nite diversity.

Sev­er­al years ago, the human genome was sequenced, 3 bil­lion chem­i­cal “let­ters,” As, Ts, Cs and Gs, in a unique arrange­ment along the human DNA. Hun­dreds of sci­en­tists around the world took part in this achieve­ment. The read­ing of the human genome was a work of mas­sive anonymity.

Knowl­edge of the struc­ture of DNA will live as long as Michelan­gelo’s Pietà, Shake­speare’s Ham­let, or Mozart’s Don Gio­van­ni, but it will endure as an anony­mous part of sci­ence. Like rel­a­tiv­i­ty, the dis­cov­ery of the code of life has pow­er for mis­chief. But it also offers a grand vision of the uni­ty of life that eclipses the work of any sin­gle artist.

If Wat­son, Crick, and Franklin had not dis­cov­ered the struc­ture of DNA, some­one else soon would have done so. We can do with­out the dis­cov­er­ers. It is incon­ceiv­able that we could do with­out the discovery.

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