An appropriate mix of art, science

An appropriate mix of art, science

Detail from “The Creation of Adam” by Michelangelo (c. 1512)

Originally published 8 February 2000

In ear­ly Decem­ber [1999], the sci­ence jour­nal Nature report­ed the sequenc­ing of the first human chro­mo­some — a com­plete tran­scrip­tion of the chem­i­cal units (nucleotides) mak­ing up the chro­mo­so­mal DNA. To cel­e­brate this impor­tant mile­stone, the edi­tor’s chose as their cov­er art a well-known detail from Michelan­gelo’s Sis­tine Chapel paint­ing The Cre­ation of Adam: the almost touch­ing fin­ger­tips of God and Adam.

In a let­ter to the edi­tor of the jour­nal, biol­o­gists Gary Har­ris and Mar­ti­na Königer of Welles­ley Col­lege take issue with the choice of illus­tra­tion, say­ing that it adds fuel to the fire in the ongo­ing bat­tle between cre­ation­ists and evo­lu­tion­ists, includ­ing the cur­rent brouha­ha over the Kansas Board of Edu­ca­tion’s deci­sion to remove evo­lu­tion from the top­ics to be cov­ered on state exams.

Does the elu­ci­da­tion of the human nucleotide sequence pro­vide us with insights into the work of the Chris­t­ian God at the cre­ation event?” they ask. And what do Chris­t­ian reli­gious sym­bols have to do with science?

The edi­tor respond­ed that the jour­nal’s staff debat­ed the use of the Michelan­ge­lo detail, but decid­ed that the image “com­bined icon­ic sym­bol­ism with the sci­ence with­out imply­ing that the Bible is true or that evo­lu­tion is not the key to mak­ing sense of biology.”

Nature’s use of Michelan­gelo’s art is appro­pri­ate. Read­ers of that jour­nal are not like­ly to take Michelan­gelo’s icon­ic image lit­er­al­ly, nor think the edi­tors are endors­ing Gen­e­sis. And mem­bers of the Kansas Board of Edu­ca­tion and their con­stituen­cies are not like­ly to be read­ers of Nature. The pos­si­bil­i­ty of adding fuel to the fire of con­tro­ver­sy seems remote.

More impor­tant, the image of Adam stretch­ing out his arm to receive from God the spark of soul is one of the most rec­og­niz­able and pow­er­ful­ly mov­ing images from all of art. It would be a shame if we were to aban­don our cul­tur­al her­itage because cer­tain parts of that her­itage have been ren­dered un-lit­er­al by progress in science.

The image on the ceil­ing of the Sis­tine Chapel does not belong only to Chris­t­ian the­ists; it belongs to all of us, and it retains even in the 21st cen­tu­ry a pow­er­ful moral significance.

Nona­ge­nar­i­an Erwin Char­gaff is one of the great bio­chemists of the 20th-cen­tu­ry. He is best known for his demon­stra­tion in the late 1940s that cer­tain chem­i­cal com­po­nents of DNA mol­e­cules always occur in con­stant ratios, a result that was cru­cial to the dis­cov­ery of the DNA dou­ble helix by James Wat­son and Fran­cis Crick. He was among the first to rec­og­nize that the chem­i­cal com­po­si­tion of DNA is species spe­cif­ic, anoth­er step on the way to elu­ci­dat­ing the struc­ture of the human genome.

In his auto­bi­og­ra­phy, Char­gaff says of his life: “In the Sis­tine Chapel, where Michelan­ge­lo depicts the cre­ation of man, God’s fin­ger and that of Adam are sep­a­rat­ed by a short space. That dis­tance I called eter­ni­ty; and there, I felt, I was sent to travel.”

Char­gaff has it exact­ly right. It is not Adam or God that are sources of the pow­er of Michelan­gelo’s paint­ing. It is the gap between their fin­gers. Michelan­ge­lo could have had God touch­ing Adam’s fin­ger. He did not. And all these cen­turies lat­er, it is the gap that draws us to the paint­ing again and again, and com­pels our fas­ci­na­tion. Although both Adam and his gray-beard­ed God have lost their lit­er­al sig­nif­i­cance, the gap between their fin­gers — between humankind and the Unname­able — remains as real and as impor­tant as ever, even to the most unmys­ti­cal and athe­is­tic scientist.

In an essay in Nature some years ago, Char­gaff charged sci­en­tists to keep their eye on the gap, to spurn the notion that they know every­thing, or even that they should know every­thing. “Sci­en­tif­ic curios­i­ty is not an unbound­ed good,” he wrote; knowl­edge is pow­er for both good and evil, and we must con­sid­er the moral impli­ca­tions of its acquisition.

This idea is deeply unpop­u­lar with­in much of the sci­en­tif­ic com­mu­ni­ty. Many sci­en­tists hold that knowl­edge itself is amoral, nei­ther good nor evil, and that to social­ly restrict the acqui­si­tion of knowl­edge is equal­ly fraught with dan­gers. Should Ein­stein have backed away from dis­cov­er­ing the equiv­a­lence of mat­ter and ener­gy because the same knowl­edge that explains how stars burn can also be used to build nuclear bombs? Should Marie Curie have fore­gone the dis­cov­ery of radi­um because some 21st-cen­tu­ry ter­ror­ist might dump radioac­tive mate­ri­als into a pub­lic water sup­ply and sick­en millions?

The elu­ci­da­tion of the human genome is knowl­edge that has stag­ger­ing poten­tial for both good and mis­chief. Few sci­en­tists would wish to retreat from its acqui­si­tion. But nei­ther should we think we have bridged the gap between our­selves and the trem­bling pow­er that resides in every liv­ing cell. “A bal­ance that does not trem­ble can­not weigh,” wrote Char­gaff; “A man who does not trem­ble can­not live.” And that’s why the Nature’s use of Michelan­gelo’s space between the fin­gers was entire­ly appropriate.

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